Citation Information :
Lonjid T, Sambuu T, Tumurbat N, Banzragch U, Dondov G, Badamjav T, Davaa B, Tudev B, Batsaikhan B. Incidence of Stomach and Esophageal Cancers in Mongolia: Data from 2009 to 2018. Euroasian J Hepatogastroenterol 2020; 10 (1):16-21.
Introduction: Digestive organ cancer is a major public health issue both in Asia and in Mongolia. The most prevalent cancer-related deaths in Mongolia are registered as caused by the stomach, esophagus, and liver. There is a lack of study which investigated the accurate incidence of digestive organ cancer nationwide. Purpose: We aimed to investigate the incidence of stomach and esophageal cancers in Mongolian population. Materials and methods: Epidemiologic data were collected between 2009 and 2018 through the oncology departments of hospitals and medical centers in all provinces, soums (the smallest unit of provinces), and major districts of the capital city. We used appropriate statistical methods in SPSS software. Results: The incidence of esophageal cancer in last 10 years (2009–2018) was 10.09 in 100,000 populations and the highest incidence was registered in Uvs (38.13), Bayan-Ulgii (24.15), and Zavkhan (18.18) provinces, respectively. The incidence of stomach cancer was 20.33 in 100,000 populations and the highest incidences were registered in Uvs (53.01), Khovd (46.02), and Darkhan-Uul (40.50) provinces, respectively. Conclusion: The incidences of these cancers have increased last 10 years in some provinces. Stomach and esophageal cancers incidence in Mongolia is considerably higher compared to the other Asian countries. The nationwide targeted prevention program is needed.
Shin H-R, Carlos MC, Varghese C. Cancer control in the Asia Pacific region: current status and concerns. Jpn J Clin Oncol 2012;42(10):867–881. DOI: 10.1093/jjco/hys077.
Chimed T, Sandagdorj T, Znaor A, et al. Cancer incidence and cancer control in Mongolia: Results from the National Cancer Registry 2008-12. Int J Cancer 2017;140(2):302–309. DOI: 10.1002/ijc.30463.
Sandagdorj T, Sanjaajamts E, Tudev U, et al. Cancer incidence and mortality in Mongolia - National Registry Data. Asian Pac J Cancer Prev 2010;11(6):1509–1514.
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68(6):394–424. DOI: 10.3322/caac.21492.
Bray F, Parkin DM. Evaluation of data quality in the cancer registry: principles and methods. Part I: comparability, validity and timeliness. Eur J Cancer 2009;45(5):747–755. DOI: 10.1016/j.ejca.2008.11.032.
MOH. National Cancer Control Program 2007-17 Mongolia. Ulaanbaatar: Ministry of Health Mongolia; 2007.
Dorzhgotov B. Risk factors in the manifestations of the 5 principal forms of cancer in the People's Republic of Mongolia. Sante Publique (Bucur) 1989;32(4):361–367.
Banks M, Graham D, Jansen M, et al. British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut 2019;68(9):1545–1575. DOI: 10.1136/gutjnl-2018-318126.
Suzuki H, Oda I, Abe S, et al. High rate of 5-year survival among patients with early gastric cancer undergoing curative endoscopic submucosal dissection. Gastric Cancer 2016;19(1):198–205. DOI: 10.1007/s10120-015-0469-0.
Jiang F, Shen X. Current prevalence status of gastric cancer and recent studies on the roles of circular RNAs and methods used to investigate circular RNAs. Cell Mol Biol Lett 2019;24(1):53. DOI: 10.1186/s11658-019-0178-5.
Health indicators. Development Center for Health. 2018.
Correa P. Helicobacter pylori infection and gastric cancer. Cancer Epidemiol Biomarkers Prev 2003;12(3):238s–241s.
Ko K-P, Shin A, Cho S, et al. Environmental contributions to gastrointestinal and liver cancer in the Asia-Pacific region. J Gastroenterol Hepatol 2018;33(1):111–120. DOI: 10.1111/jgh.14005.
Gantuya B, Bolor D, Oyuntsetseg K, et al. New observations regarding Helicobacter pylori and gastric cancer in Mongolia. Helicobacter 2018;23(4):e12491. DOI: 10.1111/hel.12491.
Matsuhisa T, Yamaoka Y, Uchida T, et al. Gastric mucosa in Mongolian and Japanese patients with gastric cancer and Helicobacter pylori infection. World J Gastroenterol 2015;21(27):8408–8417. DOI: 10.3748/wjg.v21.i27.8408.
Gantuya B, El-Serag HB, Matsumoto T, et al. Gastric microbiota in Helicobacter pylori-negative and -positive gastritis among high incidence of gastric cancer area. Cancers (Basel) 2019;11(4):504. DOI: 10.3390/cancers11040504.
Tserentogtokh T, Gantuya B, Subsomwong P, et al. Western-type Helicobacter pylori CagA are the most frequent type in Mongolian patients. Cancers (Basel) 2019;11(5):725. DOI: 10.3390/cancers11050725.
Ma S-H, Jung W, Weiderpass E, et al. Impact of alcohol drinking on gastric cancer development according to Helicobacter pylori infection status. Br J Cancer 2015;113(9):1381–1388. DOI: 10.1038/bjc.2015.333.
Humans IWGotEoCRt. Biological agents. Volume 100 B. A review of human carcinogens. IARC Monogr Eval Carcinog Risks Hum 2012. vol. 100(Pt B) pp. 1–441.
Moore MA, Sobue T. Strategies for cancer control on an organ-site basis. Asian Pac J Cancer Prev 2010;11(Suppl 2):149–164.
Malfertheiner P, Megraud F, O’Morain CA, et al. Management of Helicobacter pylori infection–the Maastricht IV/Florence Consensus Report. Gut 2012;61(5):646–664. DOI: 10.1136/gutjnl-2012-302084.
Ferlay J, Colombet M, Soerjomataram I, et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Cancer 2019;144(8):1941–1953. DOI: 10.1002/ijc.31937.
Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127(12):2893–2917. DOI: 10.1002/ijc.25516.
Park B, Yang S, Lee J, et al. Genome-wide association of genetic variation in the PSCA gene with gastric cancer susceptibility in a Korean population. Cancer Res Treat 2019;51(2):748–757. DOI: 10.4143/crt.2018.162.
Balakrishnan M, George R, Sharma A, et al. Changing trends in stomach cancer throughout the world. Curr Gastroenterol Rep 2017;19(8):36. DOI: 10.1007/s11894-017-0575-8.