Pesticides are one of the most alarming toxic substances that
are deliberately added to our environment. Carbaryl, a synthetic
1-naphthyl-N-methylcarbamate insecticide, is being used
extensively or its broad-spectrum activity in commercial
agriculture, poultry, livestock, home and garden pest control.
However, there is paucity of information about the role of carbaryl
on the liver. Wistar rats were administered with carbaryl and
the effects of this liver histology were analyzed. Profound
damage of the liver of rats administered with carbaryl was noted.
More studies would be required to assess the real implication
of this pesticide on the liver.
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Histological and ultrastructural studies of rats exposed to carbaryl. Ann Agric Environ Med 2001;8:137-44
Effect of carbaryl on some biochemical constituents of blood and liver of Clarias Batrachus, a freshwater teleost. J Toxicol Sci 1999;3:157-64
Toxic effects of dimethoate and carbaryl pesticides on reproduction and related enzymes of the fresh water snail Lymnaea acuminata. Bull Environ Contam Toxicol 2003; 71:535-42
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Induction of cytochrome P450 1A1 gene expression, oxidative stress and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells. Biochem Pharmacol 2001;61:399-407.