Euroasian journal of hepato-gastroenterology

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VOLUME 2 , ISSUE 2 ( July-December, 2012 ) > List of Articles


Acute Liver Damage and Anorexia Nervosa: A Case Report and Review of the Literature

Lionel Bridet, Juan Jose Beitia Martin, Jose Luis Cabriada Nuno

Citation Information : Bridet L, Jose Beitia Martin J, Luis Cabriada Nuno J. Acute Liver Damage and Anorexia Nervosa: A Case Report and Review of the Literature. Euroasian J Hepatogastroenterol 2012; 2 (2):104-106.

DOI: 10.5005/jp-journals-10018-1044

License: CC BY-NC 4.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2012; The Author(s).


We treated a patient suffering from severe anorexia nervosa [body mass index (BMI), 10.5 kg/m²] complicated with hepatic insufficiency. The treatment consisted of rehydration and the correction of her malnutrition, using adapted protocols to avoid the development of the refeeding syndrome. In view of her successful progress she was discharged from the hospital on day 50. Although we do not perform a hepatic biopsy, the mechanism seems to be related to autophagy more than hypoperfusion because of the extremely low BMI. This observation also highlights the need of following a multidisciplinary approach in these difficult cases (BMI < 13 kg/m²), involving intensive care unit doctors, gastroenterologists, endocrinologists and psychiatrists. Abbreviations: BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; CT: Computed tomography.

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