Insulin Resistance among Chronic Hepatitis C Patients
in Bangladesh
Salimur Rahman, Md Akmat Ali, Farida Yeasmin
Citation Information :
Rahman S, Akmat Ali M, Yeasmin F. Insulin Resistance among Chronic Hepatitis C Patients in Bangladesh. Euroasian J Hepatogastroenterol 2013; 3 (2):117-119.
Background: Insulin resistance and diabetes mellitus have
been detected in patients with chronic liver diseases (CLD);
however, there is paucity of information regarding these
comorbidities in liver disease patients of Bangladesh.
Materials and methods: Thirty patients with hepatitis B virus
(HBV)-related CLD and 30 patients with hepatitis C virus (HCV)-
related CLD were checked for existence of insulin resistance
and diabetes mellitus.
Results: The mean fasting serum glucose in HBV-related CLD
and in HCV-related CLD were 4.37 ± 0.58 and 4.6 ± 0.59 mmol/l,
respectively (p = 0.781). The levels of fasting serum insulin levels
HCV-related CLD (p = 0.013). The cutoff value of HOMA-IR was
1.73. The mean HOMA-IR of HBV- and HCV-related CLD were
1.35 ± 0.44 and 1.89 ± 0.71 respectively (p = 0.001).
Conclusion: It seems that insulin resistance is prevalent
among HCV-related CLD patients in Bangladesh. This pilot
study indicates that insulin resistance and diabetes mellitus
should be checked in all patients of HCV-related CLD during
their management.
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