Euroasian Journal of Hepato-Gastroenterology

Register      Login

VOLUME 6 , ISSUE 2 ( July-December, 2016 ) > List of Articles

CASE REPORT

A Case of Severe Ulcerative Colitis with Colonic Dilatation caused by Renal Mucinous Tubular and Spindle Cell Carcinoma

Monika Kukulska, Izabela Smola, Agnieszka Halon, Leszek Paradowski, Elzbieta Poniewierka, Radoslaw Kempinski, Abdulhabib Annabhani

Citation Information : Kukulska M, Smola I, Halon A, Paradowski L, Poniewierka E, Kempinski R, Annabhani A. A Case of Severe Ulcerative Colitis with Colonic Dilatation caused by Renal Mucinous Tubular and Spindle Cell Carcinoma. Euroasian J Hepatogastroenterol 2016; 6 (2):190-193.

DOI: 10.5005/jp-journals-10018-1198

License: CC BY-NC 4.0

Published Online: 00-00-0000


Abstract

We present a case of ulcerative colitis (UC) in a patient during the first severe relapse with colonic dilatation and coexisting of giant renal tumor. Kidney tumor was constricting on colon and imitating toxic megacolon (TM). The patient with severe acute colitis (SAC) was admitted to the Department of Gastroenterology and Hepatology with inflammatory bowel disease (IBD) diagnosed in the previous month, based on clinical symptoms, endoscopy, and histopathology results. Computed tomography (CT) revealed a giant left kidney tumor without evidence of infiltration, a dilatation of the transverse colon up to 6 cm, and narrow light of the descending colon. There were no signs of intestinal obstruction or perforation. The control X-rays revealed maintaining megacolon, with dilatation of splenic flexure projection up to 6.5 to 7.5 cm. The patient was treated conservatively with no apparent improvement and finally operated on. Intraoperatively, a large tumor of the kidney (12 cm) constricting intestine was revealed. Left-sided nephrectomy and partial resection of the colon with the emergence of a colostomy was performed. The histopathology exam revealed renal mucinous tubular and spindle cell carcinoma (RMTSCC), a very rare malignant kidney tumor of low malignant potential and relative good prognosis. It was identified in the past 20 years. To date, approximately 100 such cases of cancer have been described.


PDF Share
  1. Fornaro R, Caratto M, Barbruni G, Fornaro F, Salerno A, Giovinazzo D, Sticchi C, Caratto E. Surgical and medical treatment in patients with acute severe ulcerative colitis. J Dig Dis 2015 Oct;16(10):558-567
  2. Renal mucinous tubular and spindle cell carcinoma: a report of 8 cases and review of the literature. Diagn Pathol 2013 Dec;8:206
  3. Toxic megacolon in ulcerative colitis: a continuing challenge. Postgrad Med J 1981 Apr;57(666):223-227
  4. Surgical management of acute colitis and toxic megacolon. Clin Colon Rectal Surg 2004 Feb;17(1):71-74
  5. Toxic megacolon. Inflamm Bowel Dis 2012 Mar;18(3):584-591
  6. Toxic megacolon associated with cytomegalovirus infection in ulcerative colitis. J Gastroenterol 2003;38(11):1107-1108
  7. Mucinous tubular and spindle cell renal cell carcinoma: a review of clinicopathologic aspects. Diagn Pathol 2015 Sep;10:168
  8. Uncommon and recently described renal carcinomas. Mod Pathol 2009 Jun;22 (Suppl 2):S2-S23
  9. Spindle and cuboidal renal cell carcinoma, a tumour having frequent association with nephrolithiasis: report of 11 cases including a case with hybrid conventional renal cell carcinoma/ spindle and cuboidal renal cell carcinoma components. Histopathology 2002 Dec;41:549-455.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.