The prevalence of viral hepatitis represents Cambodia as 1 of the highest endemic countries in the
world. But the prevalence of viral hepatitis B among 5-year-olds is on a decreasing trend due to the
effect of nationwide vaccination against hepatitis B. There are key interventions to address viral hepatitis
by the Cambodian Ministry of Health. There are so far no comprehensive national guidelines for the
prevention, care, and treatment of viral hepatitis.
In 2014, the coverage of hepatitis B vaccine at birth and HepB3 vaccine was very high, at 87
and 97% respectively. Other interventions include the screening of viral hepatitis B and C among
blood donors; the enhancement of infection prevention and control at health facilities; the program
for People Who Use Drugs (PWUDs) and People Who Inject Drugs (PWIDs); control and prevention
of HIV/AIDS and sexually transmitted diseases (STDs); and improved sanitation, clean water, and
food safety.
The diagnosis of viral hepatitis B and C could be made only at the national and provincial referral
hospitals and there are no specific antiviral therapies for people who are infected with hepatitis B and C.
Thüring EG, Joller-Jemelka HI, Sareth H, Sokhan U, Reth C, Grob P. Prevalence of markers of hepatitis viruses A, B, C and of HIV in healthy individuals and patients of a Cambodian province. Southeast Asian J Trop Med Public Health 1993 Jun;24(2):239-249
High seroprevalence of hepatitis A virus Fig. 2: People Who Inject Drugs in Cambodia who sought treatment at public health facilities from 2011 to 2014 Fig. 3: High prevalence of HIV in Cambodia Bun Sreng et al 48 among migrant workers from Myanmar, Cambodia and Laos who are living in Thailand. Ann Trop Med Parasitol 2009 Jun;103(4):361-363
Hospital-based diagnosis of hemorrhagic fever, encephalitis, and hepatitis in Cambodian children. Emerg Infect Dis 2002 May;8(5):485-489
who.int/mediacentre/factsheets/ fs204/en/
Seroprevalence, genotypic distribution and potential risk factors of hepatitis B and C virus infections among adults in Siem Reap, Cambodia. Hepatol Res 2015 Apr;45(4):480-487
Molecular epidemiological study of hepatitis B virus among migrant workers from Cambodia, Laos, and Myanmar to Thailand. J Med Virol 2010 Aug;82(8):1341-1349
Results from nationwide hepatitis B serosurvey in Cambodia using simple and rapid laboratory test: implications for National Immunization Program. Am J Trop Med Hyg 2009 Aug;81(2):252-257
Prevalence of chronic hepatitis B virus infection after implementation of a hepatitis B vaccination program among children in 3 provinces in Cambodia. Vaccine 2013 Sep13;31(40):4459-4464
Prevalence of hepatitis A, B, C and E virus markers among patients with elevated levels of Alanine aminotransferase and Aspartate aminotransferase in Phnom Penh (Cambodia) and Nha Trang (Central Vietnam). Bull Soc Pathol Exot 2004 Aug;97(3):165-171
Prevalence of hepatitis B and hepatitis C virus infections in potential blood donors in rural Cambodia. Southeast Asian J Trop Med Public Health 2009 Sep;40(5):963-971
Report of the National Immunization Programme (NIP), Cambodia
