Citation Information :
Kumar Saha S, Chandra Shil B, Saha M, Parveen I. Lactose Intolerance and Symptom Pattern of Lactose Intolerance among Healthy Volunteers. Euroasian J Hepatogastroenterol 2016; 6 (1):5-7.
Aims: To see the prevalence of lactose intolerance (LI) and related symptoms following oral lactose
challenge in healthy volunteers.
Materials and methods: Symptoms of abdominal pain, nausea, borborygmi, flatulence, and diarrhea
were noted for 24 hours and blood glucose was estimated at 0 hour and 30 minutes after 25 gm oral
lactose load to healthy volunteers. Failure to rise blood glucose level ≥ 1.1 mmol/l at 30 minutes after
lactose intake from fasting level was taken as lactose malabsorption (LM), i.e., LI.
Results: A total of 166 volunteers (123 males, 43 females) with a mean age 34.78 ± 11.45 years
participated in this study. Lactose intolerance was found among 85.54% (n = 142, M = 104, F = 38). The
main symptoms of LI were diarrhea (n = 83, 58.4.0%), borborygmi (n = 81, 57.04%), abdominal pain
(n = 35, 24.65%), and flatulence (n = 27, 19.0%).
Conclusion: Lactose intolerance among healthy adults may be common in Bangladesh. Diarrhea and
borborygmi were mostly associated symptoms of LI.