Euroasian journal of hepato-gastroenterology

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VOLUME 6 , ISSUE 1 ( January-June, 2016 ) > List of Articles


Lactose Intolerance and Symptom Pattern of Lactose Intolerance among Healthy Volunteers

Shasanka Kumar Saha, Bimal Chandra Shil, Madhusudan Saha, Irin Parveen

Citation Information : Kumar Saha S, Chandra Shil B, Saha M, Parveen I. Lactose Intolerance and Symptom Pattern of Lactose Intolerance among Healthy Volunteers. Euroasian J Hepatogastroenterol 2016; 6 (1):5-7.

DOI: 10.5005/jp-journals-10018-1156

License: CC BY-NC 4.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2016; The Author(s).


Aims: To see the prevalence of lactose intolerance (LI) and related symptoms following oral lactose challenge in healthy volunteers. Materials and methods: Symptoms of abdominal pain, nausea, borborygmi, flatulence, and diarrhea were noted for 24 hours and blood glucose was estimated at 0 hour and 30 minutes after 25 gm oral lactose load to healthy volunteers. Failure to rise blood glucose level ≥ 1.1 mmol/l at 30 minutes after lactose intake from fasting level was taken as lactose malabsorption (LM), i.e., LI. Results: A total of 166 volunteers (123 males, 43 females) with a mean age 34.78 ± 11.45 years participated in this study. Lactose intolerance was found among 85.54% (n = 142, M = 104, F = 38). The main symptoms of LI were diarrhea (n = 83, 58.4.0%), borborygmi (n = 81, 57.04%), abdominal pain (n = 35, 24.65%), and flatulence (n = 27, 19.0%). Conclusion: Lactose intolerance among healthy adults may be common in Bangladesh. Diarrhea and borborygmi were mostly associated symptoms of LI.

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