A Case of Antimitochondrial Antibody Negative Primary
Biliary Cirrhosis from Bangladesh and Review of Literature
Roksana Begum, Ayub Al Mamun, Biplob Kumar Saha, Sharker Mohammad Shahadat Hossain, Dulal Chandra Das
Citation Information :
Begum R, Al Mamun A, Kumar Saha B, Mohammad Shahadat Hossain S, Chandra Das D. A Case of Antimitochondrial Antibody Negative Primary Biliary Cirrhosis from Bangladesh and Review of Literature. Euroasian J Hepatogastroenterol 2015; 5 (2):122-126.
Primary biliary cirrhosis (PBC) is very closely associated with the presence of antimitochondrial
antibodies (AMA). Nevertheless, 5 to 10% of patients with typical features of primary biliary cirrhosis
do not have detectable AMA. They are referred to as AMA negative PBC. We report a case of PBC
who was AMA-negative. The patient was a middle-aged woman seeking help of dermatologist for her
complaint of itching. The diagnosis was confirmed by histopathology, whereas other possible causes
of cirrhosis were excluded.
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