Euroasian journal of hepato-gastroenterology

Register      Login

VOLUME 5 , ISSUE 2 ( July-December, 2015 ) > List of Articles


A Case Report of Ulcerative Colitis Induced by Therapy of Colorectal Carcinoma

Tuncer Temel, Safak Meric Ozgenel, Aysegul Harmanci Ozakyol, Funda Canaz, Deniz Arik, Salih Tokmak

Citation Information : Temel T, Meric Ozgenel S, Harmanci Ozakyol A, Canaz F, Arik D, Tokmak S. A Case Report of Ulcerative Colitis Induced by Therapy of Colorectal Carcinoma. Euroasian J Hepatogastroenterol 2015; 5 (2):115-117.

DOI: 10.5005/jp-journals-10018-1148

License: CC BY-NC 4.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2015; The Author(s).


Although patients with ulcerative colitis have an increased risk for colon cancer which is associated with disease activity, location of involvement or the accompanying primary sclerosing cholangitis, ulcerative colitis induced by resections for colorectal carcinoma or chemotherapy drugs are very rare as case presentations in the literature. Fifty-nine year-old female patient with the diagnosis of sigmoid colon carcinoma have been developed ulcerative colitis 2 months after low anterior resection and oral capecitabine treatment. Development of colitis after colon cancer may be associated with some causes as mutual genetic factors that take part at the pathophysiological mechanisms liable from occurrence of ulcerative colitis and colorectal carcinoma, chemotherapy agents, perioperative stress and underlying silent ulcerative colitis. It is unclear which role is certain. Increasing reports like this case will be useful in resolving this issue.

PDF Share
  1. Herszényi L, Barabás L, Miheller P, Tulassay Z. Colorectal cancer in patients with inflammatory bowel disease: the true impact of the risk. Dig Dis 2015;33(1):52-57
  2. Mechanisms of disease: pathogenesis of Crohn’s disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol 2006;3(7):390-407
  3. Acute onset of ulcerative colitis following an operation for sigmoid colon cancer. J Gastroenterol 2006;41(1):77-82
  4. Diversion colitis: a trigger for ulcerative colitis in the in-stream colon? Gut 1999;44(2):279-282
  5. Silent ulcerative colitis adjacent to a regular sigmoid adenocarcinoma. Eur J Gastroenterol Hepatol 2011;23(10):957-960
  6. Capecitabine induced colitis. Pathol Res Pract 2014;210(9):606-608.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.