In Cambodia, the true burden of viral hepatitis has not been revealed, but many surveys were carried
out focusing on specific population or on small scales. Different markers of viral hepatitis were found
between 27 and 97% in children and almost 100% in adults. Viral hepatitis B in children was 3.5% in
2006 and dropped in 2011; and in adults, it ranged from 4.5 to 10.8%. Viral hepatitis C was between
0.87 and 14.7%. No data are available for hepatitis D in the country. Viral hepatitis E (anti-HEV IgG)
went from 7.2 to 12.7%. The complications due to viral hepatitis including chronic liver diseases and
hepatocellular carcinoma were reported in the health information system. Around 79% of the patients
with high transaminase had at least one viral marker and about 45% of the adults with chronic hepatitis
and liver cirrhosis were positive for Hepatitis B surface antigen (HBsAg). Hepatocellular carcinoma
accounted for 19.1% of all reported cancer cases. Hepatitis B surface antigen was found in between
55 and 90% in adults with hepatocellular carcinoma and anti-HCV in one-fourth. The only intervention
implemented in Cambodia is vaccination against viral hepatitis B (HepB vaccine).
Annual report of the health sector 2013 and strategic plan 2014 of Cambodia, Ministry of Health, Cambodia
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Prevalence of hepatitis A, B, C, and E virus markers among patients with elevated levels of alanine aminotransferase and aspartate aminotransferase in Phnom Penh (Cambodia) and Nha Trang (Central Vietnam). Bull Soc Pathol Exot 2004 Aug;97(3): 169-171
First detection of genotype 3 hepatitis E virus RNA in river water in Cambodia. Trans R Soc Trop Med Hyg 2009 Sep;103(9):955-957.
