Current Concepts in Hepatocellular Carcinoma and
Liver Transplantation: A Review and 2014 Update
Andrew Ofosu, Ahmet Gurakar
Citation Information :
Ofosu A, Gurakar A. Current Concepts in Hepatocellular Carcinoma and Liver Transplantation: A Review and 2014 Update. Euroasian J Hepatogastroenterol 2015; 5 (1):19-25.
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Multiple treatment
modalities for HCC are available, depending on size and number of tumor. Liver transplantation offers
the most reasonable option for curative treatment, because it simultaneously removes the burden
of the diseased liver. The Milan criteria currently remain the benchmark for the selection of patients
with HCC for transplantation. However, there is considerable and promising interest in expanding the
eligibility criteria to include the University of California San Francisco criteria. Liver transplantation
(LT) has progressed during the past decade. The introduction of living donor LT has provided a
means of expanding organ transplant, but with some inherent concerns. Herein, we reviewed the
diagnosis and management of HCC with emphasis on the current concepts of liver transplantation
for the treatment of HCC.
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