Euroasian Journal of Hepato-Gastroenterology

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VOLUME 3 , ISSUE 2 ( July-December, 2013 ) > List of Articles

ORIGINAL ARTICLE

Insulin Resistance among Chronic Hepatitis C Patients in Bangladesh

Salimur Rahman, Md Akmat Ali, Farida Yeasmin

Citation Information : Rahman S, Akmat Ali M, Yeasmin F. Insulin Resistance among Chronic Hepatitis C Patients in Bangladesh. Euroasian J Hepatogastroenterol 2013; 3 (2):117-119.

DOI: 10.5005/jp-journals-10018-1078

License: CC BY-NC 4.0

Published Online: 01-07-2013


Abstract

Background: Insulin resistance and diabetes mellitus have been detected in patients with chronic liver diseases (CLD); however, there is paucity of information regarding these comorbidities in liver disease patients of Bangladesh. Materials and methods: Thirty patients with hepatitis B virus (HBV)-related CLD and 30 patients with hepatitis C virus (HCV)- related CLD were checked for existence of insulin resistance and diabetes mellitus. Results: The mean fasting serum glucose in HBV-related CLD and in HCV-related CLD were 4.37 ± 0.58 and 4.6 ± 0.59 mmol/l, respectively (p = 0.781). The levels of fasting serum insulin levels HCV-related CLD (p = 0.013). The cutoff value of HOMA-IR was 1.73. The mean HOMA-IR of HBV- and HCV-related CLD were 1.35 ± 0.44 and 1.89 ± 0.71 respectively (p = 0.001). Conclusion: It seems that insulin resistance is prevalent among HCV-related CLD patients in Bangladesh. This pilot study indicates that insulin resistance and diabetes mellitus should be checked in all patients of HCV-related CLD during their management.


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