Euroasian Journal of Hepato-Gastroenterology

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VOLUME 3 , ISSUE 2 ( July-December, 2013 ) > List of Articles

ORIGINAL ARTICLE

Pattern of Recurrent Hepatitis C in Deceased vs Living Donor Liver Transplantation: An Egyptian Experience

Mai Ismail Mehrez, Afaf Ibrahim Farrag, Medhat Hassan El Sahhar, Shereen Shoukry Hunter, Mohamed El Beshlawy, Dalia Omran, Magdi Amin El Serafy

Citation Information : Ismail Mehrez M, Ibrahim Farrag A, Hassan El Sahhar M, Shoukry Hunter S, El Beshlawy M, Omran D, Amin El Serafy M. Pattern of Recurrent Hepatitis C in Deceased vs Living Donor Liver Transplantation: An Egyptian Experience. Euroasian J Hepatogastroenterol 2013; 3 (2):111-116.

DOI: 10.5005/jp-journals-10018-1077

License: CC BY-NC 4.0

Published Online: 01-07-2013


Abstract

Introduction: Hepatitis C virus (HCV) is the leading cause for liver transplantation (LT) and viral recurrence. Objective: Whether HCV recurrence occurs earlier and severer for living donor liver transplantation (LDLT) than for deceased donor liver transplantation (DDLT). Design: We evaluated preoperative and postoperative clinical, laboratory, and histological outcomes of 180 patients with LT (65 DDLT and 115 LDLT) since 1998 till 2006. Patients diagnosed for recurrence histologically were treated by combination therapy of pegylated interferon (IFN) and ribavirin (RBV). Results: DDLT. The mean preoperative (p = 0.012) and postoperative !\"# $ % & &\'*+ group than LDLT group. At onset of recurrence, laboratory - / 33 4 Histologically, 59.57 and 41.89% patients with DDLT and LDLT, < / / < > $ ? & &@+ E 4 / < $ G & &J+ - / - was higher in DDLT group. Conclusion: HCV recurrence rates and severity of reinfection - > - 4 3 < / / / < LDLT significantly increase the risk and severity of HCV recurrence than DDLT.


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