Euroasian Journal of Hepato-Gastroenterology

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VOLUME 3 , ISSUE 1 ( January-June, 2013 ) > List of Articles

ORIGINAL ARTICLE

Cirrhotic Cardiomyopathy in Bangladeshi Patients: A Pilot Study

Madhusudan Saha, Shasanka Kumar Saha, Ranjit Kumar Banik, Khondoker Asaduzzaman

Citation Information : Saha M, Kumar Saha S, Kumar Banik R, Asaduzzaman K. Cirrhotic Cardiomyopathy in Bangladeshi Patients: A Pilot Study. Euroasian J Hepatogastroenterol 2013; 3 (1):42-45.

DOI: 10.5005/jp-journals-10018-1061

License: CC BY-NC 4.0

Published Online: 01-01-2013


Abstract

Background: Cirrhotic cardiomyopathy is reported to be a major cause of mortality and morbidity in liver transplant recipient. It might be an emerging issue as liver transplantation has been started in Bangladesh. Materials and methods: Forty-four cirrhotic patients of varying etiology and 44 healthy volunteers were enrolled as cases and controls, respectively. Hepatic functional status was assessed by clinical examination and biochemical tests. Transthoracic echocardiography was done in both the groups. Results: Deceleration time of cirrhotic patients was significantly prolonged irrespective of etiology in comparison to controls indicating diastolic dysfunction. Left ventricular systolic diameter was also larger (significant statistically) in cirrhotic patients. Other echocardiographic parameters like E/A ratio, EF, left ventricle (LV) wall thickness, interventricular septal thickness and LV diastolic diameter showed no significant difference. Cardiac dysfunction does not depend on severity of hepatic dysfunction. Conclusion: Cirrhotic patients irrespective of cause show diastolic dysfunction. Cardiac dysfunction did not correlate the severity of hepatic dysfunction.


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