Background: Spontaneous bacterial peritonitis (SBP) is
commonly associated with cirrhosis of liver, and has been
associated with high mortality. Model for end-stage liver disease
(MELD) scoring system has been applied as a marker of
disease severity and predictor of mortality in patients with
alcoholic cirrhosis. Recent studies have estimated a prevalence
of 10 to 30% SBP in cirrhotic patients with ascites admitted to
hospitals but the data is lacking on Indian population. Hence,
the present study was designed to evaluate the profile of SBP
in patients with alcoholic cirrhosis in North India according to
MELD score.
Materials and methods: The prospective study was conducted
in patients admitted in the department of medicine. A total of
100 patients suffering from alcoholic cirrhosis with ascites were
enrolled in the study. All subjects underwent the following test
for biochemical parameters, abdominal ultrasonography, chest
X-ray, endoscopic findings and paracentesis was performed
and analyzed. MELD score was calculated for all the patients.
Results: Out of total patients, 24% reported with SBP. Patients
suffering from SBP had statistically significant (p < 0.05) higher
MELD score, International normalized ratio (INR) and serum
creatinine levels. Also, the patients with SBP had significantly
(p < 0.05) lower platelet count as compared to patients without
SBP. All the other parameters were comparable in both the
groups.
Conclusion: SBP is a common complication of alcoholic
cirrhosis of Indian patients and measures should be taken for
their containment.
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