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VOLUME 2 , ISSUE 1 ( January-June, 2012 ) > List of Articles


Spontaneous Bacterial Peritonitis in Alcoholic Cirrhosis: An Indian Perspective

Rajesh Mahajan, Prithpal Singh Matreja, Ajitpal Singh Gill, Rajoo Singh Chinna, Deepinder Kaur Chhina

Citation Information : Mahajan R, Matreja PS, Singh Gill A, Singh Chinna R, Kaur Chhina D. Spontaneous Bacterial Peritonitis in Alcoholic Cirrhosis: An Indian Perspective. Euroasian J Hepatogastroenterol 2012; 2 (1):14-19.

DOI: 10.5005/jp-journals-10018-1024

License: CC BY-NC 4.0

Published Online: 01-01-2011

Copyright Statement:  Copyright © 2012; The Author(s).


Background: Spontaneous bacterial peritonitis (SBP) is commonly associated with cirrhosis of liver, and has been associated with high mortality. Model for end-stage liver disease (MELD) scoring system has been applied as a marker of disease severity and predictor of mortality in patients with alcoholic cirrhosis. Recent studies have estimated a prevalence of 10 to 30% SBP in cirrhotic patients with ascites admitted to hospitals but the data is lacking on Indian population. Hence, the present study was designed to evaluate the profile of SBP in patients with alcoholic cirrhosis in North India according to MELD score. Materials and methods: The prospective study was conducted in patients admitted in the department of medicine. A total of 100 patients suffering from alcoholic cirrhosis with ascites were enrolled in the study. All subjects underwent the following test for biochemical parameters, abdominal ultrasonography, chest X-ray, endoscopic findings and paracentesis was performed and analyzed. MELD score was calculated for all the patients. Results: Out of total patients, 24% reported with SBP. Patients suffering from SBP had statistically significant (p < 0.05) higher MELD score, International normalized ratio (INR) and serum creatinine levels. Also, the patients with SBP had significantly (p < 0.05) lower platelet count as compared to patients without SBP. All the other parameters were comparable in both the groups. Conclusion: SBP is a common complication of alcoholic cirrhosis of Indian patients and measures should be taken for their containment.

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