Prevalence of Hepatitis B and C among Hemodialysis
Patients of Tripura, India
Kalyan Debnath, Pradip Bhaumik
Citation Information :
Debnath K, Bhaumik P. Prevalence of Hepatitis B and C among Hemodialysis Patients of Tripura, India. Euroasian J Hepatogastroenterol 2012; 2 (1):10-13.
Introduction: Hemodialysis is a trusted intermediate procedure
for management of chronic kidney disease (CKD) patients. As
such CKD is an immune-deficient state, hence, they may be
infected by hepatitis B virus (HCV) and hepatitis C virus (HCV)
during hemodialysis. Eventually, HBV and HCV infection is an
important cause of morbidity and mortality among patients of
hemodialysis. Prevalence of HBV and HCV infection among
hemodialysis patients is highly variable.
Aim of the study: This study was designed to see the
prevalence of HBV and HCV among hemodialysis patients of
Tripura, India and to evaluate the mode of transmission.
Materials and methods: This is a single center prospective
study among the patients who has come for hemodialysis at
the Dialysis Unit of Agartala Government Medical College and
Govinda Ballav Pant Hospital during the period of January 2011
to June 2011.
Results: Male predominance has been observed among the
hemodialysis patients and mean age of the patients was 48.16
years. New HBV infection was found in 5.5% of the hemodialysis
patients (cumulative 7.3%) and 10.9% (cumulative 12.12%) of
patients got new HCV infection during hemodialysis. Coinfection
with both HBV and HCV was found among 1.2% of
hemodialysis patients. History of blood transfusion was found
in 100% of newly infected HBV and HCV patients.
Discussion: The evaluation suggests that blood transfusion
may be the single most important risk factor for HBV and HCV
infection among hemodialysis patients. Newer methods of
screening of blood in blood bank like nucleic acid test or
polymerase chain reaction amplification of nucleic acids should
be adopted to prevent HBV and HCV transmission
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