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VOLUME 13 , ISSUE 1 ( January-June, 2023 ) > List of Articles

Original Article

Retrospective Investigation of Factors Affecting Mortality in Spontaneous Bacterial Peritonitis

Tuğba Ocak, Macit Gülten

Keywords : Cirrhosis, Mortality, Peritonitis

Citation Information : Ocak T, Gülten M. Retrospective Investigation of Factors Affecting Mortality in Spontaneous Bacterial Peritonitis. Euroasian J Hepatogastroenterol 2023; 13 (1):5-9.

DOI: 10.5005/jp-journals-10018-1387

License: CC BY-NC 4.0

Published Online: 03-08-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Background: Spontaneous bacterial peritonitis (SBP) is an important reason for mortality in cirrhosis. This study aimed to identify the factors associated with mortality in SBP. Materials and methods: A total of 69 patients with cirrhosis and 74 with SBP attacks that occurred in this group were assessed. Demographic data, symptoms at admission, comorbidities, laboratory parameters, treatment protocols, causes of cirrhosis, scoring characteristics, cirrhosis complications, and mortality were analyzed. Results: Model for end-stage liver disease (MELD; p = 0.001), sodium-MELD (p = 0.001), and Child–Pugh–Turcotte (CTP) (p < 0.001) scores were correlated with mortality in patients with SBP episodes. Hepatorenal syndrome (p = 0.001) and esophageal variceal bleeding (p < 0.001) related to mortality. Serum lactate dehydrogenase (LDH) (p = 0.007), serum leukocyte (p = 0.017), and serum hemoglobin (p = 0.010) values had a statistically significant effect on mortality in multivariate regression analysis. Discussion: The mortality rate can be reduced by identifying factors influencing death in patients with SBP episodes.

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