Euroasian journal of hepato-gastroenterology

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VOLUME 12 , ISSUE 1 ( January-June, 2022 ) > List of Articles


Mixed Neuroendocrine – Nonneuroendocrine Neoplasm Arising in Barrett's Esophagus

Soon Liang Lee, Chiun Yann Ng, Lai Teck Gew, Jasminder Sidhu, Zuliatul F Baharom

Keywords : Barrett's esophagus, Esophageal adenocarcinoma, Neuroendocrine neoplasm

Citation Information : Lee SL, Ng CY, Gew LT, Sidhu J, Baharom ZF. Mixed Neuroendocrine – Nonneuroendocrine Neoplasm Arising in Barrett's Esophagus. Euroasian J Hepatogastroenterol 2022; 12 (1):57-59.

DOI: 10.5005/jp-journals-10018-1356

License: CC BY-NC 4.0

Published Online: 13-07-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Barrett's esophagus, which results from chronic gastroesophageal reflux disease, is a known precursor to dysplasia and ultimately esophageal adenocarcinoma. Mixed neuroendocrine – nonneuroendocrine neoplasm (MiNEN) is a rare and heterogenous group of neoplasm with aggressive clinical behavior in general. There have been rare reports of MiNEN arising in Barrett's esophagus, and its pathogenesis remains unclear. Surgical resection with lymph node dissection remains the most effective treatment of MiNEN of the esophagus to date, although the evidence on its optimal treatment is scant.

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