Euroasian Journal of Hepato-Gastroenterology

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VOLUME 10 , ISSUE 1 ( January-June, 2020 ) > List of Articles


Helicobacter pylori Infection and Gastric Microbiota

Gokben Ozbey, Emma Sproston, Alfizah Hanafiah

Keywords : Gastric microbiota, Helicobacter pylori, Stomach

Citation Information : Ozbey G, Sproston E, Hanafiah A. Helicobacter pylori Infection and Gastric Microbiota. Euroasian J Hepatogastroenterol 2020; 10 (1):36-41.

DOI: 10.5005/jp-journals-10018-1310

License: CC BY-NC 4.0

Published Online: 22-08-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Owing to its strong acid production, the stomach was known to be a bacteria-free organ for many years. On the other hand, the presence of Helicobacter pylori (H. pylori) and other acid-resistant microbiota that are to persist in the stomach challenged this. It is now recognized that the existence of H. pylori and non-H. pylori species have been linked to the improvement of gastric disease; despite this, there is little published data on the interaction of gastric bacterial flora and the resultant effect on gastric health. The stomach has a unique microbiota including five major phyla, such as Firmicutes, Proteobacteria, Actinobacteria, Fusobacteria and Bacteroidetes. These phyla are identified in both H. pylori-infected and uninfected persons. The resident gastric microflora may mediate the role of H. pylori in the gastric diseases. This article aims to review previous studies that examine the impact of H. pylori infection and the effect of resident gastric microbiota on gut health and disease conditions.

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