Euroasian journal of hepato-gastroenterology

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VOLUME 1 , ISSUE 1 ( January-June, 2011 ) > List of Articles


Effects of Plain and Blended Indian Pan Masala on Murine Liver

Suresh Kumar Nigam, Huthi Venkatakrishna Bhatt

Citation Information : Kumar Nigam S, Venkatakrishna Bhatt H. Effects of Plain and Blended Indian Pan Masala on Murine Liver. Euroasian J Hepatogastroenterol 2011; 1 (1):27-29.

DOI: 10.5005/jp-journals-10018-1006

License: CC BY-NC 4.0

Published Online: 01-09-2010

Copyright Statement:  Copyright © 2011; The Author(s).


Chronic consumption of pan masala plain (PMP) or with tobacco (PMT) cause liver injury. Three groups of mice of both sexes consuming PMP, PMT and control diet for prolonged period were enrolled in this study. Blood samples were collected 16, 56 and 70 weeks after study commencement and checked for serum alkaline phosphotase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase. Significant increased levels of all these enzymes were found in mice provided with PMP and PMT compared to control mice, however, elevation in the intermittent samples varied between PMP and PMT groups. This study has indicated the liver injury potential of pan masala and their effects should be assessed in human.

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